ID   C22 (Clara)
AC   CVCL_F277
SY   C22
DR   ABM; T0092
DR   ECACC; 07021401
DR   Wikidata; Q54808099
RX   PubMed=12026164;
WW   Provider; SLU; 98-008; https://www.slu.edu/research/faculty-resources/research-innovation-group/browse-ip/research-tools/98-008-c22-a-conditionally-immortalized-mouse-clara-cell-line.php
CC   Characteristics: Proliferates at permissive temperature (33 Celsius) in the presence of IFNG, terminally differentiates at restrictive temperature (39 Celsius) in the absence of IFNG.
CC   Doubling time: 48 hours (ECACC=07021401).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Club cell; CL=CL_0000158.
CC   Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Conditionally immortalized cell line
DT   Created: 22-10-12; Last updated: 14-08-25; Version: 14
//
RX   PubMed=12026164; DOI=10.1290/1071-2690(2002)038<0154:GACOAC>2.0.CO;2;
RA   deMello, Daphne E.
RA   Mahmoud, Sohir
RA   Ryerse, Jan
RA   Hoffmann, Joseph W.
RT   "Generation and characterization of a conditionally immortalized lung
RT   Clara cell line from the H-2Kb-tsA58 transgenic mouse.";
RL   In Vitro Cell. Dev. Biol. Anim. 38:154-164(2002).
//