ID   HEK293T METTL18 KO METTL18-HA
AC   CVCL_F1XG
SY   METTL18 KO HEK293T with stable METTL18 expression
RX   PubMed=35674491;
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28793; METTL18.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:28793; METTL18 (Note=With a C-terminal HA tag).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_F1XD ! HEK293T METTL18 KO
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//
RX   PubMed=35674491; DOI=10.7554/eLife.72780; PMCID=PMC9177149;
RA   Matsuura-Suzuki, Eriko
RA   Shimazu, Tadahiro
RA   Takahashi, Mari
RA   Kotoshiba, Kaoru
RA   Suzuki, Takehiro
RA   Kashiwagi, Kazuhiro
RA   Sohtome, Yoshihiro
RA   Akakabe, Mai
RA   Sodeoka, Mikiko
RA   Dohmae, Naoshi
RA   Ito, Takuhiro
RA   Shinkai, Yoichi
RA   Iwasaki, Shintaro
RT   "METTL18-mediated histidine methylation of RPL3 modulates translation
RT   elongation for proteostasis maintenance.";
RL   eLife 11:e72780.1-e72780.33(2022).
//