ID   HyCyte BxPC-3 KO-hDTNBP1
AC   CVCL_F1NG
SY   hDTNBP1 knockout BxPC-3
DR   Hysigen; CGKO-M2747
CC   Population: Caucasian.
CC   Doubling time: 36-48 hours (Hysigen=CGKO-M2747).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:17328; DTNBP1.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple_edited; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous; Note=By CRISPR/Cas9 (Hysigen=CGMU-M2185).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0186 ! BxPC-3
SX   Female
AG   61Y
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
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