ID   U-87MG EMC10 isoform HSS1
AC   CVCL_F1JR
SY   U87 pcDNA3.1-hHSS1
RX   PubMed=20680400;
CC   Problematic cell line: Misidentified. Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala.
CC   Population: Caucasian.
CC   Doubling time: 32.1 hours (PubMed=20680400).
CC   Sequence variation: Mutation; HGNC; HGNC:7765; NF1; Simple; p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT); ClinVar=VCV000420078; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; c.209+1G>T; ClinVar=VCV000229705; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:27609; EMC10 (Note=Isoform HSS1).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0022 ! U-87MG ATCC
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//
RX   PubMed=20680400; DOI=10.1007/s11060-010-0314-6; PMCID=PMC3052511;
RA   Junes-Gill, Katiana S.
RA   Gallaher, Timothy K.
RA   Gluzman-Poltorak, Zoya
RA   Miller, Joseph D.
RA   Wheeler, Christopher J.
RA   Fan, Xue-Mo
RA   Basile, Lena A.
RT   "hHSS1: a novel secreted factor and suppressor of glioma growth
RT   located at chromosome 19q13.33.";
RL   J. Neurooncol. 102:197-211(2011).
//