ID   MB135
AC   CVCL_F1IZ
RX   PubMed=28171552;
RX   PubMed=29533181;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Thigh, quadriceps skeletal muscle; UBERON=UBERON_0004498.
CC   Cell type: Myoblast; CL=CL_0000056.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Telomerase immortalized cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
CH   CVCL_F1JH ! MB135-iDUX4
//
RX   PubMed=28171552; DOI=10.1093/hmg/ddw271; PMCID=PMC6078597;
RA   Jagannathan, Sujatha
RA   Shadle, Sean C.
RA   Resnick, Rebecca
RA   Snider, Lauren D.
RA   Tawil, Rabi Nabil
RA   van der Maarel, Silvere Maria
RA   Bradley, Robert K.
RA   Tapscott, Stephen Justice
RT   "Model systems of DUX4 expression recapitulate the transcriptional
RT   profile of FSHD cells.";
RL   Hum. Mol. Genet. 25:4419-4431(2016).
//
RX   PubMed=29533181; DOI=10.7554/eLife.31023; PMCID=PMC5849414;
RA   Campbell, Amy E.
RA   Shadle, Sean C.
RA   Jagannathan, Sujatha
RA   Lim, Jong-Won
RA   Resnick, Rebecca
RA   Tawil, Rabi Nabil
RA   van der Maarel, Silvere Maria
RA   Tapscott, Stephen Justice
RT   "NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by
RT   DUX4-induced MBD3L proteins.";
RL   eLife 7:e31023.1-e31023.27(2018).
//