ID   K-562 GATA2 clone G2-4
AC   CVCL_F0X5
SY   G2-4
RX   PubMed=11146164;
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4171; GATA2.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
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RX   PubMed=11146164; DOI=10.1016/s0301-472x(00)00553-1;
RA   Ikonomi, Pranvera
RA   Rivera, Candido E.
RA   Riordan, Michael
RA   Washington, Glennelle Clark
RA   Schechter, Alan Neil
RA   Noguchi, Constance Tom
RT   "Overexpression of GATA-2 inhibits erythroid and promotes
RT   megakaryocyte differentiation.";
RL   Exp. Hematol. 28:1423-1431(2000).
//