ID   CHL V-79 RJK
AC   CVCL_F0SV
SY   V-79 RJK
RX   DOI=10.1134/S1990519X15050028;
RX   DOI=10.1134/S1990519X21010041;
RX   PubMed=8754132;
RX   PubMed=38338745;
CC   Selected for resistance to: ChEBI; CHEBI_472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
CC   Selected for resistance to: ChEBI; CHEBI_472805; Ouabain.
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_2234 ! V79
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
CH   CVCL_F0XE ! Vebr-10
CH   CVCL_F0SW ! Vebr-2
CH   CVCL_F0SX ! Vebr-20
CH   CVCL_F0XF ! Vebr-25
CH   CVCL_F0XG ! Vebr-30
CH   CVCL_F0SY ! Vebr-5
//
RX   PubMed=8754132;
RA   Grinchuk, Tatiana M.
RA   Lipskaia, L.A.
RA   Artsybasheva, I.V.
RA   Sorokina, Elena A.
RA   Pan'shina, I.T.
RA   Ignatova, Tatyana N.
RT   "The karyotypic variability of Chinese hamster CHLV-79 RJK cells
RT   characterized by multiple drug resistance resulting from the
RT   amplification of the mdr gene family.";
RL   Tsitologiia 38:161-172(1996).
//
RX   DOI=10.1134/S1990519X15050028;
RA   Agafonova, Nina A.
RA   Grinchuk, Tatiana M.
RA   Korablev, Vladimir V.
RA   Rozanov, Yuri Mikhailovich
RA   Sakuta, Galina Anatolyevna
RA   Shilina, Mariia A.
RA   Shtein, Gregory I.
RA   Kudryavtsev, Boris N.
RT   "DNA content of individual chromosomes of Chinese hamster normal
RT   karyotype and its permanent cell lines V-79 RJK and Verb-5.";
RL   Cell Tissue Biol. 9:371-376(2015).
//
RX   PubMed=38338745; DOI=10.3390/ijms25031467; PMCID=PMC10855830;
RA   Shorokhova, Mariia A.
RA   Pugovkina, Natalia A.
RA   Zemelko, Victoria I.
RA   Lyublinskaya, Olga G.
RA   Grinchuk, Tatiana M.
RT   "Long-term cryopreservation may cause genomic instability and the
RT   premature senescence of cells.";
RL   Int. J. Mol. Sci. 25:1467.1-1467.12(2024).
//
RX   DOI=10.1134/S1990519X21010041;
RA   Grinchuk, Tatiana M.
RA   Alekseenko, Larisa L.
RA   Shilina, Mariia A.
RA   Ivanova, Valentina P.
RT   "Short-term exposure of RJK cells with multiple drug resistance to
RT   polyallylaminane destabilizes their karyotype structure.";
RL   Cell Tissue Biol. 15:98-106(2021).
//