ID   U2OS-TMEM192-3xHA
AC   CVCL_F0QI
SY   U2OS:TMEM192-3xHA
RX   DOI=10.1101/2023.09.11.557213;
CC   Population: Caucasian.
CC   Characteristics: Transfected with a pLJC5-Tmem192-3xHA construct (DOI=10.1101/2023.09.11.557213).
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:26775; TMEM192 (Note=With a 3xHA tag).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 27-11-25; Last updated: 27-11-25; Version: 1
//
RX   DOI=10.1101/2023.09.11.557213;
RA   Nguyen, Mai
RA   Collier, Jack J.
RA   Ignatenko, Olesia
RA   Morin, Genevieve
RA   Huang, Si-Dong
RA   Desjardins, Michel
RA   McBride, Heidi M.
RT   "Parkinson's genes orchestrate pyroptosis through selective
RT   trafficking of mtDNA to leaky lysosomes.";
RL   bioRxiv 2023:09.11.557213-09.11.557213(2023).
//