ID   V79MZr2E1
AC   CVCL_F0FW
SY   V79r2e1
RX   DOI=10.1080/10406639908020586;
RX   PubMed=10335445;
RX   PubMed=16221041;
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=RGD; 2475; Cyp2e1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   DOI=10.1080/10406639908020586;
RA   Jacob, Juergen
RA   Raab, Gottfried
RA   Soballa, Volker J.
RA   Luch, Andreas
RA   Grimmer, Gernot
RA   Greim, Helmut
RA   Doehmer, Johannes
RA   Morrison, Hilary Gonzalez
RA   Stegeman, John Joseph
RA   Seidel, Albrecht
RT   "Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a,
RT   l]pyrene by various CYP450 isoforms.";
RL   Polycycl. Aromat. Compd. 16:191-203(2000).
//
RX   PubMed=10335445; DOI=10.1081/dmr-100101928;
RA   Doehmer, Johannes
RA   Buters, Jeroen Titus Maria
RA   Luch, Andreas
RA   Soballa, Volker J.
RA   Baird, William M.
RA   Morrison, Hilary Gonzalez
RA   Stegeman, John Joseph
RA   Townsend, Alan J.
RA   Greenlee, William F.
RA   Glatt, Hans-Ruedolf
RA   Seidel, Albrecht
RA   Jacob, Juergen
RA   Greim, Helmut
RT   "Molecular studies on the toxifying effects by genetically engineered
RT   cytochromes P450.";
RL   Drug Metab. Rev. 31:423-435(1999).
//
RX   PubMed=16221041; DOI=10.1177/026119290303100104;
RA   Bernauer, Ulrike
RA   Glatt, Hans-Ruedolf
RA   Heinrich-Hirsch, Barbara
RA   Liu, Yun-Gang
RA   Muckel, Eva
RA   Vieth, Barbel
RA   Gundert-Remy, Ursula
RT   "Heterologous expression of mouse cytochrome P450 2e1 in V79 cells:
RT   construction and characterisation of the cell line and comparison
RT   with V79 cell lines stably expressing rat P450 2E1 and human P450
RT   2E1.";
RL   Altern. Lab. Anim. 31:21-30(2003).
//