ID   V79MZh2D6*2
AC   CVCL_F0FJ
RX   Patent=US20050130116;
RX   PubMed=12947487;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); ACC-2447.
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2625; CYP2D6 (Note=With p.Arg296Cys (c.886C>T). Allele CYP2D6*2).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   Patent=US20050130116;
RA   Doehmer, Johannes
RA   Krebsfaenger, Niels
RA   Eichelbaum, Michel F.
RA   Zanger, Ulrich M.
RT   "Stable expression of polymorphous forms of human cytochrome p450
RT   2D6.";
RL   Patent number US20050130116, 16-Jun-2005.
//
RX   PubMed=12947487;
RA   Krebsfaenger, Niels
RA   Murdter, Thomas E.
RA   Zanger, Ulrich M.
RA   Eichelbaum, Michel F.
RA   Doehmer, Johannes
RT   "V79 Chinese hamster cells genetically engineered for polymorphic
RT   cytochrome P450 2D6 and their predictive value for humans.";
RL   ALTEX 20:143-154(2003).
//