ID   V79MZh3A4
AC   CVCL_F0FE
SY   V79MZh3A4(SV)
RX   DOI=10.1080/10406639908020586;
RX   PubMed=8806738;
RX   PubMed=10335445;
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2637; CYP3A4.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   DOI=10.1080/10406639908020586;
RA   Jacob, Juergen
RA   Raab, Gottfried
RA   Soballa, Volker J.
RA   Luch, Andreas
RA   Grimmer, Gernot
RA   Greim, Helmut
RA   Doehmer, Johannes
RA   Morrison, Hilary Gonzalez
RA   Stegeman, John Joseph
RA   Seidel, Albrecht
RT   "Species-dependent metabolism of benzo[c]phenanthrene and dibenzo[a,
RT   l]pyrene by various CYP450 isoforms.";
RL   Polycycl. Aromat. Compd. 16:191-203(2000).
//
RX   PubMed=8806738; DOI=10.1006/abbi.1996.0345;
RA   Schneider, Anneliese
RA   Schmalix, Wolfgang A.
RA   Siruguri, Vasanthi
RA   de Groene, Els M.
RA   Horbach, G. Jean
RA   Kleingeist, Britta
RA   Lang, Dieter
RA   Bocker, Ronald
RA   Belloc, Claire
RA   Beaune, Philippe
RA   Greim, Helmut
RA   Doehmer, Johannes
RT   "Stable expression of human cytochrome P450 3A4 in conjunction with
RT   human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster
RT   cells.";
RL   Arch. Biochem. Biophys. 332:295-304(1996).
//
RX   PubMed=10335445; DOI=10.1081/dmr-100101928;
RA   Doehmer, Johannes
RA   Buters, Jeroen Titus Maria
RA   Luch, Andreas
RA   Soballa, Volker J.
RA   Baird, William M.
RA   Morrison, Hilary Gonzalez
RA   Stegeman, John Joseph
RA   Townsend, Alan J.
RA   Greenlee, William F.
RA   Glatt, Hans-Ruedolf
RA   Seidel, Albrecht
RA   Jacob, Juergen
RA   Greim, Helmut
RT   "Molecular studies on the toxifying effects by genetically engineered
RT   cytochromes P450.";
RL   Drug Metab. Rev. 31:423-435(1999).
//