ID   HL-60 eosinophilic subline No. 3(5)
AC   CVCL_F0CS
RX   PubMed=3486011;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7961; Adult acute myeloid leukemia with maturation
DI   ORDO; Orphanet_98834; Acute myeloblastic leukemia with maturation
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_F0CQ ! HL-60 eosinophilic subline No. 3
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
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RX   PubMed=3486011; DOI=10.1182/blood.V67.5.1433.1433;
RA   Tomonaga, Masao
RA   Gasson, Judith C.
RA   Quan, Shirley G.
RA   Golde, David W.
RT   "Establishment of eosinophilic sublines from human promyelocytic
RT   leukemia (HL-60) cells: demonstration of multipotentiality and
RT   single-lineage commitment of HL-60 stem cells.";
RL   Blood 67:1433-1441(1986).
//