ID   huSP
AC   CVCL_F0A3
RX   PubMed=2982143;
CC   Population: Japanese.
CC   Virology: Contains multiple copies of integrated hepatitis B virus (HBV) genomes. Compared to parent cell line, has a higher production of hepatitis B surface antigen. Produces no HBV core or E antigens (PubMed=2982143).
CC   Sequence variation: Mutation; HGNC; HGNC:903; AXIN1; Simple; p.Asn302Profs*111 (c.904_907delAACC); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Leu (c.329G>T); ClinVar=VCV000406597; Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2956 ! HuH-1
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   PubMed=2982143; DOI=10.1073/pnas.82.1.208; PMCID=PMC397001;
RA   Mizusawa, Hiroshi
RA   Taira, Masanori
RA   Yaginuma, Katsuyuki
RA   Kobayashi, Midori
RA   Yoshida, Eisaku
RA   Koike, Katsuro
RT   "Inversely repeating integrated hepatitis B virus DNA and cellular
RT   flanking sequences in the human hepatoma-derived cell line huSP.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:208-212(1985).
//