ID   UCSD232i-SAD2-1
AC   CVCL_EJ93
SY   sAD2.1; SAD2.1; UCSD-ADRC#3093-1
DR   SKIP; SKIP005439
DR   WiCell; ucsd232i-sad2-1
DR   Wikidata; Q54990038
RX   PubMed=22278060;
RX   PubMed=30686764;
CC   Population: Caucasian.
CC   Discontinued: WiCell; ucsd232i-sad2-1; true.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2866; Alzheimer's disease
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_1N91 ! UCSD233i-SAD2-2
OI   CVCL_EJ94 ! UCSD234i-SAD2-3
OI   CVCL_EJ95 ! UCSD235i-SAD2-4
SX   Male
AG   83Y
CA   Induced pluripotent stem cell
DT   Created: 26-09-16; Last updated: 29-06-23; Version: 12
//
RX   PubMed=22278060; DOI=10.1038/nature10821;
RA   Israel M.A., Yuan S.H., Bardy C., Reyna S.M., Mu Y.-L., Herrera C.M.,
RA   Hefferan M.P., Van Gorp S.F.J., Nazor K.L., Boscolo F.S., Carson C.T.,
RA   Laurent L.C., Marsala M., Gage F.H., Remes A.M., Koo E.H.,
RA   Goldstein L.S.B.;
RT   "Probing sporadic and familial Alzheimer's disease using induced
RT   pluripotent stem cells.";
RL   Nature 482:216-220(2012).
//
RX   PubMed=30686764; DOI=10.1016/j.stem.2018.12.013;
RA   van der Kant R., Langness V.F., Herrera C.M., Williams D.A.,
RA   Fong L.K., Leestemaker Y., Steenvoorden E., Rynearson K.D.,
RA   Brouwers J.F., Helms J.B., Ovaa H., Giera M., Wagner S.L., Bang A.G.,
RA   Goldstein L.S.B.;
RT   "Cholesterol metabolism is a druggable axis that independently
RT   regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease
RT   neurons.";
RL   Cell Stem Cell 24:363-375.e9(2019).
//