ID   C100
AC   CVCL_EI66
SY   C100M
DR   GEO; GSM4178086
DR   Wikidata; Q54807812
RX   PubMed=22250051;
RX   PubMed=22383533;
CC   Characteristics: Early passage culture.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly469Arg (c.1405G>A); ClinVar=VCV000177775; Zygosity=Heterozygous (PubMed=22383533).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Arg88Gln (c.263G>A); ClinVar=VCV000376049; Zygosity=Heterozygous (PubMed=22383533).
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-04-25; Version: 7
//
RX   PubMed=22250051; DOI=10.1002/gcc.21932;
RA   Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S.,
RA   O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D.,
RA   O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A.,
RA   Hayward N.K.;
RT   "Identification of TFG (TRK-fused gene) as a putative metastatic
RT   melanoma tumor suppressor gene.";
RL   Genes Chromosomes Cancer 51:452-461(2012).
//
RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
//