ID   C097
AC   CVCL_EI65
DR   cancercelllines; CVCL_EI65
DR   Wikidata; Q54807770
RX   PubMed=22250051;
RX   PubMed=22383533;
CC   Characteristics: Early passage culture.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=22383533).
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-04-25; Version: 8
//
RX   PubMed=22250051; DOI=10.1002/gcc.21932;
RA   Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S.,
RA   O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D.,
RA   O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A.,
RA   Hayward N.K.;
RT   "Identification of TFG (TRK-fused gene) as a putative metastatic
RT   melanoma tumor suppressor gene.";
RL   Genes Chromosomes Cancer 51:452-461(2012).
//
RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
//