ID   C086
AC   CVCL_EI60
SY   C086M
DR   Cosmic; 1665194
DR   Cosmic; 2465276
DR   GEO; GSM4178080
DR   Wikidata; Q54807645
RX   PubMed=22250051;
RX   PubMed=22383533;
RX   PubMed=23890154;
CC   Characteristics: Early passage culture.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; None_reported; -; Zygosity=- (PubMed=22383533).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   27Y
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-04-25; Version: 8
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RX   PubMed=22250051; DOI=10.1002/gcc.21932;
RA   Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S.,
RA   O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D.,
RA   O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A.,
RA   Hayward N.K.;
RT   "Identification of TFG (TRK-fused gene) as a putative metastatic
RT   melanoma tumor suppressor gene.";
RL   Genes Chromosomes Cancer 51:452-461(2012).
//
RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
//
RX   PubMed=23890154; DOI=10.1111/pcmr.12153;
RA   Dutton-Regester K., Kakavand H., Aoude L.G., Stark M.S.,
RA   Gartside M.G., Johansson P., O'Connor L., Lanagan C., Tembe V.,
RA   Pupo G.M., Haydu L.E., Schmidt C.W., Mann G.J., Thompson J.F.,
RA   Scolyer R.A., Hayward N.K.;
RT   "Melanomas of unknown primary have a mutation profile consistent with
RT   cutaneous sun-exposed melanoma.";
RL   Pigment Cell Melanoma Res. 26:852-860(2013).
//