ID   C042
AC   CVCL_EI44
DR   cancercelllines; CVCL_EI44
DR   Cosmic; 1665188
DR   Wikidata; Q54800058
RX   PubMed=22250051;
RX   PubMed=22383533;
CC   Characteristics: Early passage culture.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=22250051; PubMed=22383533).
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B4KJ ! C042-2
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-04-25; Version: 11
//
RX   PubMed=22250051; DOI=10.1002/gcc.21932;
RA   Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S.,
RA   O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D.,
RA   O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A.,
RA   Hayward N.K.;
RT   "Identification of TFG (TRK-fused gene) as a putative metastatic
RT   melanoma tumor suppressor gene.";
RL   Genes Chromosomes Cancer 51:452-461(2012).
//
RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
//