ID   MBU-Ts4
AC   CVCL_EG15
SY   MBU-TS4; Ts4
DR   DSMZ; ACC-801
DR   DSMZCellDive; ACC-801
DR   GEO; GSM1687269
DR   GEO; GSM1687270
DR   GEO; GSM1687271
DR   Wikidata; Q54904162
RX   PubMed=27074337;
CC   Characteristics: Derived from a xenograft produced by injection of the parent cell line in nude mice.
CC   Doubling time: ~80-100 hours (DSMZ=ACC-801).
CC   Karyotypic information: 47,XY,+20 [5]; 46,XY,-13,+20 [3]; 47,XY,-13,+20,+mar [3] (PubMed=27074337).
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
ST   Source(s): DSMZ=ACC-801
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 8,11
ST   D16S539: 11,12
ST   D18S51: 13,15
ST   D19S433: 13,14
ST   D21S11: 29,33.2
ST   D2S1338: 24
ST   D3S1358: 16,17
ST   D5S818: 10,12
ST   D7S820: 8,11
ST   D8S1179: 12,13
ST   FGA: 20,22
ST   Penta D: 9,14
ST   Penta E: 10,14
ST   TH01: 8,9.3
ST   TPOX: 8
ST   vWA: 13,15
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_EG13 ! MBU-T
SX   Male
AG   <1D
CA   Transformed cell line
DT   Created: 13-07-16; Last updated: 10-04-25; Version: 14
//
RX   PubMed=27074337; DOI=10.1002/ijc.30139;
RA   Cantarino N., Fernandez-Figueras M.T., Valero V., Musulen E.,
RA   Malinverni R., Granada I., Goldie S.J., Martin-Caballero J., Douet J.,
RA   Forcales S.-V., Buschbeck M.;
RT   "A cellular model reflecting the phenotypic heterogeneity of mutant
RT   HRAS driven squamous cell carcinoma.";
RL   Int. J. Cancer 139:1106-1116(2016).
//