ID   U87MG-Venus-Akaluc
AC   CVCL_E9YE
RX   PubMed=33241215;
CC   Population: Caucasian.
CC   Characteristics: Transduced with a hPGK-Venus-Akaluc-WPRE-mPGK-Neo construct (PubMed=33241215).
CC   Sequence variation: Mutation; HGNC; HGNC:7765; NF1; Simple; p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT); ClinVar=VCV000420078; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; c.209+1G>T; ClinVar=VCV000229705; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=FPbase; YUJWJ; Venus (Note=Bright yellow fluorescent protein derived from GFP).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=Photinus pyralis Akaluciferase (Akaluc) (Note=A luciferase-derived fluorescent protein).
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0022 ! U-87MG ATCC
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
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RX   PubMed=33241215; DOI=10.1093/noajnl/vdaa134; PMCID=PMC7680182;
RA   Bozec, Dominique
RA   Sattiraju, Anirudh
RA   Bouras, Alexandros
RA   Jesu Raj, Joe Gerald
RA   Rivera, Daniel
RA   Huang, Yong
RA   Junqueira Alves, Chrystian
RA   Tejero, Rut
RA   Tsankova, Nadejda M.
RA   Zou, Hong-Yan
RA   Hadjipanayis, Constantinos
RA   Friedel, Roland Horst
RT   "Akaluc bioluminescence offers superior sensitivity to track in vivo
RT   glioma expansion.";
RL   Neurooncol. Adv. 2:vdaa134.1-vdaa134.10(2020).
//