ID   HEI286
AC   CVCL_E9BY
SY   HEI-286; HEI 286; House Ear Institute 286
DR   GEO; GSM5481587
DR   GEO; GSM5481588
DR   GEO; GSM5481589
DR   GEO; GSM5481590
RX   CelloPub=CLPUB00805;
RX   PubMed=20178741;
RX   PubMed=26999607;
RX   PubMed=35881881;
CC   Doubling time: 38 hours (CelloPub=CLPUB00805).
CC   Karyotypic information: Hypo-triploid male (XO) with most chromosome counts in the 60-68 range (CelloPub=CLPUB00805).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptomics; Microarray.
CC   Donor information: Established from an acoustic neuroma patient (CelloPub=CLPUB00805).
CC   Miscellaneous: STR profile from personal communication of Stupakov, Pavel.
CC   Derived from site: In situ; Peripheral nervous system, vestibular nerve; UBERON=UBERON_0003723.
CC   Cell type: Schwann cell; CL=CL_0002573.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 14
ST   D16S539: 14
ST   D18S51: 17
ST   D21S11: 31,31.2
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 9,10
ST   D8S1179: 10,13
ST   FGA: 21,22
ST   Penta D: 12,13
ST   Penta E: 16
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 15,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   61Y
CA   Transformed cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   CelloPub=CLPUB00805;
RA   Andalibi, Ali
RT   "Establish an in vitro model for the study of NF2 gene function and
RT   gene therapy.";
RL   (In misc. document) Report for award DAMD17-99-1-9491. Defense Technical Information Center document ADA431978; pp.1-52; DTIC; Fort Belvoir; USA (2004).
//
RX   PubMed=20178741; DOI=10.1016/j.cell.2010.01.029; PMCID=PMC2828953;
RA   Li, Wei
RA   You, Li-Ru
RA   Cooper, Jonathan E.
RA   Schiavon, Gaia
RA   Pepe-Caprio, Angela
RA   Zhou, Lu
RA   Ishii, Ryohei
RA   Giovannini, Marco
RA   Hanemann, Clemens Oliver
RA   Long, Stephen B.
RA   Erdjument-Bromage, Hediye
RA   Zhou, Peng-Bo
RA   Tempst, Paul
RA   Giancotti, Filippo G.
RT   "Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin
RT   ligase CRL4(DCAF1) in the nucleus.";
RL   Cell 140:477-490(2010).
//
RX   PubMed=26999607; DOI=10.1172/JCI82658; PMCID=PMC4811155;
RA   Deborde, Sylvie
RA   Omelchenko, Tatiana
RA   Lyubchik, Anna
RA   Zhou, Yi
RA   He, Shi-Zhi
RA   McNamara, William Francis
RA   Chernichenko, Natalya
RA   Lee, Sei-Young
RA   Barajas, Fernando
RA   Chen, Chun-Hao
RA   Bakst, Richard L.
RA   Vakiani, Efsevia
RA   He, Shuang-Ba
RA   Hall, Alan
RA   Wong, Richard J.
RT   "Schwann cells induce cancer cell dispersion and invasion.";
RL   J. Clin. Invest. 126:1538-1554(2016).
//
RX   PubMed=35881881; DOI=10.1158/2159-8290.CD-21-1690; PMCID=PMC9533012;
RA   Deborde, Sylvie
RA   Gusain, Laxmi
RA   Powers, Ann
RA   Marcadis, Andrea R.
RA   Yu, Ya-Song
RA   Chen, Chun-Hao
RA   Frants, Anna
RA   Kao, Elizabeth
RA   Tang, Laura H.
RA   Vakiani, Efsevia
RA   Amisaki, Masataka
RA   Balachandran, Vinod P.
RA   Calo, Annalisa
RA   Omelchenko, Tatiana
RA   Jessen, Kristjan R.
RA   Reva, Boris A.
RA   Wong, Richard J.
RT   "Reprogrammed Schwann cells organize into dynamic tracks that promote
RT   pancreatic cancer invasion.";
RL   Cancer Discov. 12:2454-2473(2022).
//