ID   HEK-Blue IL-1beta v2
AC   CVCL_E8DC
DR   InvivoGen; hkb-il1bv2
CC   Characteristics: Designed to detect bioactive human and mouse IL1B monitoring the activation of the NF-kappaB and AP-1 pathways. In addition, the TNF-alpha, TLR3 and TLR5 responses have been blocked (InvivoGen=hkb-il1bv2).
CC   Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB and AP-1-binding sites (InvivoGen=hkb-il1bv2).
CC   Knockout cell: Method=Not specified; HGNC; HGNC:11849; TLR3.
CC   Knockout cell: Method=Not specified; HGNC; HGNC:11851; TLR5.
CC   Knockout cell: Method=Not specified; HGNC; HGNC:11916; TNFRSF1A.
CC   Knockout cell: Method=Not specified; HGNC; HGNC:11917; TNFRSF1B.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A7YL ! HEK-Blue Null1-v
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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