ID   Hs 578T Hcg-11
AC   CVCL_E8BU
SY   Hcg-11
RX   PubMed=7949216;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012612; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val157Phe (c.469G>T); ClinVar=VCV000012353; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Ala135Val = p53Val135).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0332 ! Hs 578T
SX   Female
AG   74Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=7949216; DOI=10.1007/BF00666061;
RA   Eliyahu D., Evans S., Rosen N., Eliyahu S., Zwiebel J.A., Paik S.,
RA   Lippman M.E.;
RT   "p53Val135 temperature sensitive mutant suppresses growth of human
RT   breast cancer cells.";
RL   Breast Cancer Res. Treat. 30:167-177(1994).
//