ID   15/40
AC   CVCL_E8B9
RX   DOI=10.1016/B978-012442710-5.50265-3;
RX   PubMed=7620321;
RX   PubMed=9914916;
RX   PubMed=19273061;
WW   Provider; URMC; -; https://www.urmc.rochester.edu/microbiology-immunology/research/xenopus-laevis/models/cell-lines
CC   Group: Amphibian cell line.
CC   Characteristics: Expresses low level of MHC class I and MHC class II molecules (DOI=10.1016/B978-012442710-5.50265-3; PubMed=9914916).
CC   Characteristics: Tumorigenic in larval and adult syngeneic hosts (DOI=10.1016/B978-012442710-5.50265-3; PubMed=9914916).
CC   Characteristics: Displays a dual B-cell and T-cell phenotype (PubMed=9914916).
CC   Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: LG-15.
DI   NCIt; C215148; Xenopus thymic lymphoma
OX   NCBI_TaxID=8355; ! Xenopus laevis (African clawed frog)
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   DOI=10.1016/B978-012442710-5.50265-3;
RA   Robert J., Du Pasquier L.;
RT   "Xenopus lymphoid tumor cell lines.";
RL   (In book chapter) Immunology methods manual. The comprehensive sourcebook of techniques, Vol. 2; Lefkovits I. (eds.); pp.2367-2377; Academic Press; New York; USA (1996).
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RX   PubMed=7620321; DOI=10.1155/1994/37392; PMCID=PMC2275934;
RA   Robert J., Guiet C., Du Pasquier L.;
RT   "Lymphoid tumors of Xenopus laevis with different capacities for
RT   growth in larvae and adults.";
RL   Dev. Immunol. 3:297-307(1994).
//
RX   PubMed=9914916; DOI=10.1111/j.1600-065x.1998.tb01266.x;
RA   Robert J., Cohen N.;
RT   "Evolution of immune surveillance and tumor immunity: studies in
RT   Xenopus.";
RL   Immunol. Rev. 166:231-243(1998).
//
RX   PubMed=19273061; DOI=10.2741/3238; PMCID=PMC2749489;
RA   Goyos A., Robert J.;
RT   "Tumorigenesis and anti-tumor immune responses in Xenopus.";
RL   Front. Biosci. 14:167-176(2009).
//