ID   K1735-C4
AC   CVCL_E7ZF
SY   K-1735 C4; K-1735 clone 4; K1735C4; C4; C4.P
RX   PubMed=6944560;
RX   PubMed=7535333;
WW   Provider; MD Anderson CCAC; -; https://www.mdanderson.org/content/dam/mdanderson/documents/core-facilities/Cytogenetics-and-Cell-Authentication-Core/Cell%20Line%20List%203-23-2022.pdf
CC   Characteristics: Highly metastatic. Produces melanotic lung metastases in syngeneic mice.
CC   Sequence variation: Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCIt; C17231; Ultraviolet radiation.
CC   Breed/subspecies: C3H/HeN.
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_F828 ! K1735
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=6944560; DOI=10.1093/jnci/67.4.947;
RA   Fidler I.J., Gruys E., Cifone M.A., Barnes Z., Bucana C.D.;
RT   "Demonstration of multiple phenotypic diversity in a murine melanoma
RT   of recent origin.";
RL   J. Natl. Cancer Inst. 67:947-956(1981).
//
RX   PubMed=7535333; DOI=10.1084/jem.181.4.1333; PMCID=PMC2191958;
RA   Xie K.-P., Huang S.-Y., Dong Z.-Y., Juang S.-H., Gutman M., Xie Q.-W.,
RA   Nathan C.F., Fidler I.J.;
RT   "Transfection with the inducible nitric oxide synthase gene suppresses
RT   tumorigenicity and abrogates metastasis by K-1735 murine melanoma
RT   cells.";
RL   J. Exp. Med. 181:1333-1343(1995).
//