ID   HEK-293 rCTR C1a clone F12
AC   CVCL_E7XD
SY   F12
RX   PubMed=7723741;
RX   PubMed=10517675;
CC   Characteristics: Expresses ~60,000 receptors/cell (PubMed=7723741).
CC   Genetic integration: Method=Transfection; Gene=RGD; 621001; Calcr (Note=Isoform C1a).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=7723741; DOI=10.1016/S0026-895X(25)08628-6;
RA   Houssami S., Findlay D.M., Brady C.L., Martin T.J., Epand R.M., Moore E.E.,
RA   Murayama E., Tamura T., Orlowski R.C., Sexton P.M.;
RT   "Divergent structural requirements exist for calcitonin receptor
RT   binding specificity and adenylate cyclase activation.";
RL   Mol. Pharmacol. 47:798-809(1995).
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RX   PubMed=10517675; DOI=10.1210/mend.13.10.0359;
RA   Evdokiou A., Raggatt L.-J., Atkins G.J., Findlay D.M.;
RT   "Calcitonin receptor-mediated growth suppression of HEK-293 cells is
RT   accompanied by induction of p21WAF1/CIP1 and G2/M arrest.";
RL   Mol. Endocrinol. 13:1738-1750(1999).
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