ID   U2OS mEGFP-LplA
AC   CVCL_E7RP
RX   PubMed=40069234;
CC   Population: Caucasian.
CC   Characteristics: Transduced with a pCDH-mEGFP-LplA construct (PubMed=40069234).
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=FPbase; QKFJN; mEGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P32099; Escherichia coli lipoate-protein ligase A (lplA).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=40069234; DOI=10.1038/s41467-025-57886-4;
RA   Nie J.-L., Zhang X.-Y., Hu Z.-J., Wang W., Schroer M.A., Ren J.,
RA   Svergun D.I., Chen A.-Y., Yang P.-G., Zeng A.-P.;
RT   "A globular protein exhibits rare phase behavior and forms chemically
RT   regulated orthogonal condensates in cells.";
RL   Nat. Commun. 16:2449-2449(2025).
//