ID   Ephb266
AC   CVCL_E7G1
RX   PubMed=20639864;
CC   Characteristics: Transduced with an EphB2-IRES-RFP construct. Transduced cells were implanted into the cerebral cortex of CD-1 nu/nu mice and the cell line was established from a tumor (PubMed=20639864).
CC   Knockout cell: Method=KO mouse; MGI; MGI:104738; Cdkn2a.
CC   Genetic integration: Method=Transduction; Gene=FPbase; TXLFX; DsRed2 (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:99611; Ephb2.
CC   Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Derived from site: In situ; Embryonic brain, forebrain; UBERON=UBERON_0006240.
CC   Cell type: Neural stem cell; CL=CL_0000047.
CC   Breed/subspecies: Ink4a/Arf-null Blbp-eGFP transgenic.
DI   NCIt; C21951; Mouse ependymoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   14-15FD
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=20639864; DOI=10.1038/nature09173; PMCID=PMC2912966;
RA   Johnson R.A., Wright K.D., Poppleton H., Mohankumar K.M.,
RA   Finkelstein D.B., Pounds S.B., Rand V., Leary S.E.S., White E.L., Eden C.,
RA   Hogg T.L., Northcott P.A., Mack S.C., Neale G., Wang Y.-D., Coyle B.,
RA   Atkinson J., DeWire M.D., Kranenburg T.A., Gillespie G.Y., Allen J.C.,
RA   Merchant T.E., Boop F.A., Sanford R.A., Gajjar A., Ellison D.W.,
RA   Taylor M.D., Grundy R.G., Gilbertson R.J.;
RT   "Cross-species genomics matches driver mutations and cell compartments
RT   to model ependymoma.";
RL   Nature 466:632-636(2010).
//