ID   VDS-0
AC   CVCL_E7E3
SY   VDS-O; VDSO; VDSO/parental; VDSO/P
RX   PubMed=3018084;
RX   PubMed=9563901;
RX   PubMed=9973220;
CC   Characteristics: Seems to be composed of immature B cells. Does not secretes Ig nor contains intracellular Ig (PubMed=3018084).
CC   Doubling time: 28 hours (PubMed=9563901).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E7E8 ! VDS
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=3018084; DOI=10.4049/jimmunol.137.6.2037;
RA   Tosato G., Marti G.E., Yarchoan R., Heilman C.A., Wang F., Pike S.E.,
RA   Korsmeyer S.J., Siminovitch K.A.;
RT   "Epstein-Barr virus immortalization of normal cells of B cell lineage
RT   with nonproductive, rearranged immunoglobulin genes.";
RL   J. Immunol. 137:2037-2042(1986).
//
RX   PubMed=9563901;
RA   Fan S.-J., Cherney B.W., Reinhold W.C., Rucker K., O'Connor P.M.;
RT   "Disruption of p53 function in immortalized human cells does not
RT   affect survival or apoptosis after taxol or vincristine treatment.";
RL   Clin. Cancer Res. 4:1047-1054(1998).
//
RX   PubMed=9973220;
RA   Gutierrez M.I., Cherney B.W., Hussain A., Mostowski H.S., Tosato G.,
RA   Magrath I.T., Bhatia K.G.;
RT   "Bax is frequently compromised in Burkitt's lymphomas with
RT   irreversible resistance to Fas-induced apoptosis.";
RL   Cancer Res. 59:696-703(1999).
//