ID   OME1
AC   CVCL_E6Z3
DR   ABM; T0415
RX   PubMed=32433794;
RX   PubMed=37899851;
CC   Population: Caucasian.
CC   Doubling time: 48-72 hours (ABM=T0415).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Donor information: Established from a patient with otitis media and mild 40 dB hearing loss (PubMed=37899851).
CC   Caution: The same name is used for the primary culture described in PubMed=32433794 and the immortalized cell line described in PubMed=37899851.
CC   Derived from site: In situ; Ear, middle ear; UBERON=UBERON_0001756.
CC   Cell type: Epithelial cell; CL=CL_0000066.
DI   NCIt; C34885; Otitis media
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   2Y8M
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=32433794; DOI=10.1002/lary.28687;
RA   Espahbodi M., Samuels T.L., McCormick C., Khampang P., Yan K.,
RA   Marshall S., McCormick M.E., Chun R.H., Harvey S.A., Friedland D.R.,
RA   Johnston N., Kerschner J.E.;
RT   "Analysis of inflammatory signaling in human middle ear cell culture
RT   models of pediatric otitis media.";
RL   Laryngoscope 131:410-416(2021).
//
RX   PubMed=37899851; DOI=10.1002/lio2.1141; PMCID=PMC10601576;
RA   Blaine-Sauer S., Samuels T.L., Khampang P., Yan K., McCormick M.E.,
RA   Chun R.H., Harvey S.A., Friedland D.R., Johnston N., Kerschner J.E.;
RT   "Establishment of novel immortalized middle ear cell lines as models
RT   for otitis media.";
RL   Laryngoscope Investig. Otolaryngol. 8:1428-1435(2023).
//