ID   UM-SCC-12-Luc-YFP
AC   CVCL_E6YS
SY   UMSCC12Luc
RX   PubMed=22265717;
CC   Characteristics: Transfected with a luciferase-YFP fusion protein whose expression is under the control of a CMV promoter (PubMed=22265717).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln104Ter (c.310C>T); ClinVar=VCV000566924; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP).
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7717 ! UM-SCC-12
SX   Male
AG   71Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=22265717; DOI=10.1016/j.oraloncology.2011.12.012; PMCID=PMC3350825;
RA   Martin C.K., Dirksen W.P., Shu S.T., Werbeck J.L., Thudi N.K.,
RA   Yamaguchi M., Wolfe T.D., Heller K.N., Rosol T.J.;
RT   "Characterization of bone resorption in novel in vitro and in vivo
RT   models of oral squamous cell carcinoma.";
RL   Oral Oncol. 48:491-499(2012).
//