ID   Ba/F3 FLT3-ITD-Y842C [Malmo]
AC   CVCL_E6YC
DR   ABM; T3681
RX   PubMed=38001685;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3765; FLT3 (Note=With ITD and p.Tyr842Cys).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Pro-B cell; CL=CL_0000826.
CC   Breed/subspecies: C3H.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0161 ! Ba/F3
CA   Factor-dependent cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=38001685; DOI=10.3390/cancers15225426; PMCID=PMC10670458;
RA   Kazi J.U., Al Ashiri L., Purohit R., Ronnstrand L.;
RT   "Understanding the role of activation loop mutants in drug efficacy
RT   for FLT3-ITD.";
RL   Cancers (Basel) 15:5426.1-5426.14(2023).
//