ID   Ba/F3 FLT3-ITD [Malmo]
AC   CVCL_E6Y7
RX   PubMed=19438505;
RX   PubMed=28271164;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3765; FLT3 (Note=With ITD).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Pro-B cell; CL=CL_0000826.
CC   Breed/subspecies: C3H.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0161 ! Ba/F3
CA   Factor-dependent cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=19438505; DOI=10.1111/j.1365-2141.2009.07725.x;
RA   Masson K., Liu T., Khan R., Sun J.-M., Ronnstrand L.;
RT   "A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation
RT   and cell survival.";
RL   Br. J. Haematol. 146:193-202(2009).
//
RX   PubMed=28271164; DOI=10.1007/s00018-017-2494-0; PMCID=PMC5487891;
RA   Kazi J.U., Chougule R.A., Li T.-F., Su X.-W., Moharram S.A., Rupar K.,
RA   Marhall A., Gazi M., Sun J.-M., Zhao H., Ronnstrand L.;
RT   "Tyrosine 842 in the activation loop is required for full
RT   transformation by the oncogenic mutant FLT3-ITD.";
RL   Cell. Mol. Life Sci. 74:2679-2688(2017).
//