ID   Ba/F3 KIT isoform 2
AC   CVCL_E6Y0
SY   Ba/F3 c-KIT GNNK- WT
DR   ABM; T3041
RX   PubMed=17904548;
RX   PubMed=18697750;
RX   PubMed=26040420;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6342; KIT (Note=Isoform 2 = GNNK-).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Caution: The parent cell line was originally thought to originate from a BALB/c mouse but is in fact from a C3H mouse.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Pro-B cell; CL=CL_0000826.
CC   Breed/subspecies: C3H.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0161 ! Ba/F3
CA   Factor-dependent cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=17904548; DOI=10.1016/j.yexcr.2007.08.021;
RA   Sun J.-M., Pedersen M., Bengtsson S., Ronnstrand L.;
RT   "Grb2 mediates negative regulation of stem cell factor receptor/c-Kit
RT   signaling by recruitment of Cbl.";
RL   Exp. Cell Res. 313:3935-3942(2007).
//
RX   PubMed=18697750; DOI=10.1074/jbc.M709703200;
RA   Sun J.-M., Pedersen M., Ronnstrand L.;
RT   "Gab2 is involved in differential phosphoinositide 3-kinase signaling
RT   by two splice forms of c-Kit.";
RL   J. Biol. Chem. 283:27444-27451(2008).
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RX   PubMed=26040420; DOI=10.1007/s00018-015-1944-9; PMCID=PMC11113438;
RA   Lindblad O., Kazi J.U., Ronnstrand L., Sun J.-M.;
RT   "PI3 kinase is indispensable for oncogenic transformation by the V560D
RT   mutant of c-Kit in a kinase-independent manner.";
RL   Cell. Mol. Life Sci. 72:4399-4407(2015).
//