ID   NiAC
AC   CVCL_E5VH
SY   Non-OA iAC; Non-OA immortalized Articular Chondrocytes
DR   ABM; T0384
RX   PubMed=36647698;
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Donor information: Established from a patient that had a hip fracture (PubMed=36647698).
CC   Derived from site: In situ; Femoral head, cartilage; UBERON=UBERON_8480062.
CC   Cell type: Chondrocyte; CL=CL_0000138.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   81Y
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 14-08-25; Version: 2
//
RX   PubMed=36647698; DOI=10.1302/2046-3758.121.BJR-2022-0207.R1; PMCID=PMC9872042;
RA   Pineiro-Ramil, Maria
RA   Sanjurjo-Rodriguez, Clara
RA   Rodriguez-Fernandez, Silvia
RA   Hermida-Gomez, Tamara
RA   Blanco-Garcia, Francisco Javier
RA   Fuentes-Boquete, Isaac Manuel
RA   Vaamonde-Garcia, Carlos
RA   Diaz-Prado, Silvia Maria
RT   "Generation of human immortalized chondrocytes from osteoarthritic and
RT   healthy cartilage: a new tool for cartilage pathophysiology studies.";
RL   Bone Joint Res. 12:46-57(2023).
//