ID   iMC37
AC   CVCL_E5UX
DR   ABM; T0320
RX   PubMed=22592154;
CC   Characteristics: Intermediately differentiated melanoblasts (PubMed=22592154).
CC   Characteristics: Transduced with a SSR#41 vector (LTR-FRT-HygR-HSV1-TK-IRES-SV40LT-FRT-Neo-LTR) that allows removal of the SV40 TAg by using FLP (PubMed=22592154).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Melanocyte of skin; CL=CL_1000458.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   <1D
CA   Conditionally immortalized cell line
DT   Created: 10-04-25; Last updated: 14-08-25; Version: 2
//
RX   PubMed=22592154; DOI=10.1038/jid.2012.145; PMCID=PMC4083699;
RA   Yang, Ke
RA   Chen, Jin
RA   Jiang, Wei
RA   Huang, En-Yi
RA   Cui, Jing
RA   Kim, Stephanie H.
RA   Hu, Ning
RA   Liu, Hong
RA   Zhang, Wen-Wen
RA   Li, Rui-Dong
RA   Chen, Xiang
RA   Kong, Yu-Han
RA   Zhang, Ji-Ye
RA   Wang, Jin-Hua
RA   Wang, Lin-Yuan
RA   Shen, Ji-Kun
RA   Luu, Hue H.
RA   Haydon, Rex Charles
RA   Lian, Xiao-Hua
RA   Yang, Tian
RA   He, Tong-Chuan
RT   "Conditional immortalization establishes a repertoire of mouse
RT   melanocyte progenitors with distinct melanogenic differentiation
RT   potential.";
RL   J. Invest. Dermatol. 132:2479-2483(2012).
//