ID   FRTL5-Ras-Backbone Vector clone 8
AC   CVCL_E5UE
SY   FR-BV8; BV8
RX   PubMed=27125250;
RX   PubMed=30744101;
CC   Characteristics: Control cell line for the FRTL5-Ras-PATZ1 cell lines (PubMed=27125250).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
CC   Breed/subspecies: Fischer 344; RS=RS_0000215.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_E5TY ! FRTL-5 H-RAS(V12) clone V29
SX   Sex unspecified
AG   6W
CA   Spontaneously immortalized cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=27125250; DOI=10.1038/srep25268; PMCID=PMC4850481;
RA   Vitiello M., Valentino T., De Menna M., Crescenzi E., Francesca P.,
RA   Rea D., Arra C., Fusco A., De Vita G., Cerchia L., Fedele M.;
RT   "PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in
RT   rat thyroid cells.";
RL   Sci. Rep. 6:25268.1-25268.10(2016).
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RX   PubMed=30744101; DOI=10.3390/genes10020127; PMCID=PMC6410289;
RA   Vitiello M., Palma G., Monaco M., Bello A.M., Camorani S., Francesca P.,
RA   Rea D., Barbieri A., Chiappetta G., De Vita G., Cerchia L., Arra C.,
RA   Fedele M.;
RT   "Dual oncogenic/anti-oncogenic role of PATZ1 in FRTL5 rat thyroid
RT   cells transformed by the Ha-Ras V12 oncogene.";
RL   Genes (Basel) 10:127.1-127.13(2019).
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