ID   U2OS E2F7 KO
AC   CVCL_E5FF
DR   CancerTools; 156469
RX   PubMed=29590434;
CC   Population: Caucasian.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:23820; E2F7.
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=29590434; DOI=10.1093/nar/gky218; PMCID=PMC5961008;
RA   Mitxelena J., Apraiz A., Vallejo-Rodriguez J., Garcia-Santisteban I.,
RA   Fullaondo A., Alvarez-Fernandez M., Malumbres M., Zubiaga Elordieta A.M.;
RT   "An E2F7-dependent transcriptional program modulates DNA damage repair
RT   and genomic stability.";
RL   Nucleic Acids Res. 46:4546-4559(2018).
//