ID   ZR-75-1 BCAR3 clone B3-10
AC   CVCL_E4WU
SY   ZR-75-1 BCAR3 [B3-10]
DR   CancerTools; 154622
RX   PubMed=9582273;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:973; BCAR3.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 10-04-25; Version: 2
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RX   PubMed=9582273; DOI=10.1093/emboj/17.10.2799; PMCID=PMC1170620;
RA   van Agthoven T., van Agthoven T.L.A., Dekker A., van der Spek P.J.,
RA   Vreede L., Dorssers L.C.J.;
RT   "Identification of BCAR3 by a random search for genes involved in
RT   antiestrogen resistance of human breast cancer cells.";
RL   EMBO J. 17:2799-2808(1998).
//