ID   CHO SSF3
AC   CVCL_E4HJ
SY   CHOSSF3; SSF3
RX   DOI=10.3929/ethz-a-000888370;
RX   PubMed=8549740;
RX   PubMed=9634782;
RX   PubMed=10516577;
CC   Group: Serum/protein free medium cell line.
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
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RX   DOI=10.3929/ethz-a-000888370;
RA   Gandor C.R.;
RT   "Establishment and characterization of growth-factor-prototrophic
RT   Chinese hamster ovary (CHO) cell lines for the production of
RT   recombinant proteins.";
RL   Thesis PhD (1993); Swiss Federal Institute of Technology Zurich; Zurich; Switzerland.
//
RX   PubMed=8549740; DOI=10.1016/0014-5793(95)01328-8;
RA   Gandor C.R., Leist C.H., Fiechter A., Asselbergs F.A.M.;
RT   "Amplification and expression of recombinant genes in
RT   serum-independent Chinese hamster ovary cells.";
RL   FEBS Lett. 377:290-294(1995).
//
RX   PubMed=9634782; DOI=10.1038/nbt0495-389;
RA   Zang-Gandor M.O., Trautmann H., Gandor C.R., Messi F.,
RA   Asselbergs F.A.M., Leist C.H., Fiechter A., Reiser J.;
RT   "Production of recombinant proteins in Chinese hamster ovary cells
RT   using a protein-free cell culture medium.";
RL   Biotechnology (N.Y.) 13:389-392(1995).
//
RX   PubMed=10516577; DOI=10.1002/(SICI)1097-0290(19991205)65:5<523::AID-BIT4>3.0.CO;2-6;
RA   Gandor C.R., Zang-Gandor M.O., Flor P.J., Marangi M.,
RA   Asselbergs F.A.M.;
RT   "Conditionally adherent growth of serum-independent CHO cells for
RT   automated drug screening and biopharmaceutical production.";
RL   Biotechnol. Bioeng. 65:523-528(1999).
//