ID   FT246-YAP(S127A)
AC   CVCL_E3FH
SY   FT246-YAPS127A
RX   PubMed=26364602;
CC   Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11998; TP53.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:16262; YAP1 (Note=With p.Ser127Ala).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
CC   Cell type: Fallopian tube secretory epithelial cell; CL=CL_4030006.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_UH61 ! FT246
SX   Female
AG   Age unspecified
CA   Telomerase immortalized cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
//
RX   PubMed=26364602; DOI=10.1038/onc.2015.288; PMCID=PMC4791205;
RA   Hua G.-H., Lv X.-M., He C.-B., Remmenga S.W., Rodabaugh K.J.,
RA   Dong J.-X., Yang L., Lele S.M., Yang P., Zhou J., Karst A.M.,
RA   Drapkin R.I., Davis J.S., Wang C.;
RT   "YAP induces high-grade serous carcinoma in fallopian tube secretory
RT   epithelial cells.";
RL   Oncogene 35:2247-2265(2016).
//