ID   KB-ChR-8
AC   CVCL_E3EU
SY   KB-8
RX   PubMed=2897240;
RX   PubMed=3711108;
CC   Problematic cell line: Contaminated. Ancestral cell line (KB) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI_23359; Colchicine.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2088 ! KB-3-1
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 10-04-25; Version: 2
//
RX   PubMed=2897240; DOI=10.1016/0092-8674(88)90568-5;
RA   Choi K.H., Chen C.-J., Kriegler M., Roninson I.B.;
RT   "An altered pattern of cross-resistance in multidrug-resistant human
RT   cells results from spontaneous mutations in the mdr1 (P-glycoprotein)
RT   gene.";
RL   Cell 53:519-529(1988).
//
RX   PubMed=3711108; DOI=10.1016/S0021-9258(19)57466-X;
RA   Shen D.-W., Cardarelli C., Hwang J., Cornwell M., Richert N., Ishii S.,
RA   Pastan I., Gottesman M.M.;
RT   "Multiple drug-resistant human KB carcinoma cells independently
RT   selected for high-level resistance to colchicine, adriamycin, or
RT   vinblastine show changes in expression of specific proteins.";
RL   J. Biol. Chem. 261:7762-7770(1986).
//