ID   H9/R7hyg
AC   CVCL_E3D8
RX   PubMed=7523570;
CC   Population: Caucasian.
CC   Characteristics: Transfected with plasmid R7hyg containing a human immunodeficiency virus 1 (HIV-1) isolate HXB2 proviral clone containing HygR in place of the HIV-1 nef gene (PubMed=7523570).
CC   Sequence variation: Gene deletion; HGNC; HGNC:7208; MPDZ; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C3366; Sezary syndrome
DI   ORDO; Orphanet_3162; Sezary syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1240 ! H9
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 19-12-24; Version: 2
//
RX   PubMed=7523570; DOI=10.1084/jem.180.4.1283; PMCID=PMC2191672;
RA   Tsomides T.J., Aldovini A., Johnson R.P., Walker B.D., Young R.A.,
RA   Eisen H.N.;
RT   "Naturally processed viral peptides recognized by cytotoxic T
RT   lymphocytes on cells chronically infected by human immunodeficiency
RT   virus type 1.";
RL   J. Exp. Med. 180:1283-1293(1994).
//