ID   F20T
AC   CVCL_E2X3
RX   PubMed=33157036;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Donor information: Established from a patient undergoing corneal transplant surgery (PubMed=33157036).
CC   Derived from site: In situ; Eye, cornea, endothelium; UBERON=UBERON_0001985.
CC   Cell type: Endothelial cell of cornea; CL=CL_0000132.
DI   NCIt; C84721; Fuchs endothelial dystrophy
DI   ORDO; Orphanet_98974; Fuchs endothelial corneal dystrophy
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   54Y
CA   Transformed cell line
DT   Created: 10-09-24; Last updated: 14-08-25; Version: 3
//
RX   PubMed=33157036; DOI=10.1016/j.chembiol.2020.10.007; PMCID=PMC7855261;
RA   Angelbello, Alicia J.
RA   Benhamou, Raphael Isaac
RA   Rzuczek, Suzanne G.
RA   Choudhary, Shruti
RA   Tang, Zhen-Zhi
RA   Chen, Jonathan L.
RA   Roy, Madhuparna
RA   Wang, Kye Won
RA   Yildirim, Ilyas
RA   Jun, Albert Suk
RA   Thornton, Charles Allan
RA   Disney, Matthew David
RT   "A small molecule that binds an RNA repeat expansion stimulates its
RT   decay via the exosome complex.";
RL   Cell Chem. Biol. 28:34-45.e6(2021).
//