ID   HCA2 [Human foreskin fibroblast]
AC   CVCL_E2UW
SY   HCA 2
DR   GEO; GSE198396
RX   PubMed=7753810;
RX   PubMed=9310070;
RX   PubMed=36323784;
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Fibroblast of foreskin; CL=CL_1001608.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   <1M
CA   Finite cell line
DT   Created: 10-09-24; Last updated: 10-04-25; Version: 2
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RX   PubMed=7753810; DOI=10.1073/pnas.92.10.4352; PMCID=PMC41942;
RA   Nakanishi M., Adami G.R., Robetorye R.S., Noda A., Venable S.F.,
RA   Dimitrov D., Pereira-Smith O.M., Smith J.R.;
RT   "Exit from G0 and entry into the cell cycle of cells expressing
RT   p21Sdi1 antisense RNA.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:4352-4356(1995).
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RX   PubMed=9310070; DOI=10.1093/gerona/52a.5.b229;
RA   Rubelj I., Venable S.F., Lednicky J., Butel J.S., Bilyeu T.,
RA   Darlington G.J., Surmacz E., Campisi J., Pereira-Smith O.M.;
RT   "Loss of T-antigen sequences allows SV40-transformed human cells in
RT   crisis to acquire a senescent-like phenotype.";
RL   J. Gerontol., A, Biol. Sci. Med. Sci. 52:B229-B234(1997).
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RX   PubMed=36323784; DOI=10.1038/s41586-022-05388-4;
RA   Wang T.-W., Johmura Y., Suzuki N., Omori S., Migita T., Yamaguchi K.,
RA   Hatakeyama S., Yamazaki S., Shimizu E., Imoto S., Furukawa Y.,
RA   Yoshimura A., Nakanishi M.;
RT   "Blocking PD-L1-PD-1 improves senescence surveillance and ageing
RT   phenotypes.";
RL   Nature 611:358-364(2022).
//