ID   HP-18b
AC   CVCL_E2TD
RX   PubMed=23245717;
CC   Population: Caucasian.
CC   Biotechnology: Used in assay systems for the detection of HPA-18b antibodies (PubMed=23245717).
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6137; ITGA2 (Note=With p.Gln735His = HPA-18b/Cab(a)).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 10-04-25; Version: 3
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RX   PubMed=23245717; DOI=10.2450/2012.0126-12; PMCID=PMC3934277;
RA   Hayashi T., Amakishi E., Matsuyama N., Yasui K., Furuta R.A., Hori Y.,
RA   Tanaka S., Fukumori Y., Hirayama F.;
RT   "Detection of anti-human platelet antibodies against integrin
RT   alpha2beta1 using cell lines.";
RL   Blood Transfus. 12 Suppl. 1:s273-s280(2014).
//