ID   A7 [Rat optic nerve astrocyte]
AC   CVCL_E148
DR   Wikidata; Q54607185
RX   PubMed=3053737;
RX   PubMed=7583324;
RX   PubMed=8076662;
RX   PubMed=10516297;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Central nervous system, optic nerve; UBERON=UBERON_0000941.
CC   Cell type: Astrocyte; CL=CL_0000127.
CC   Breed/subspecies: Sprague Dawley; RS=RS_0000681.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 16
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RX   PubMed=3053737; DOI=10.1083/jcb.107.5.1977; PMCID=PMC2115320;
RA   Geller H.M., Dubois-Dalcq M.;
RT   "Antigenic and functional characterization of a rat central nervous
RT   system-derived cell line immortalized by a retroviral vector.";
RL   J. Cell Biol. 107:1977-1986(1988).
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RX   PubMed=7583324; DOI=10.1016/0006-8993(95)00575-B;
RA   Fok-Seang J., Smith-Thomas L.C., Meiners S., Muir E., Du J.-S.,
RA   Housden E., Johnson A.R., Faissner A., Geller H.M., Keynes R.J.,
RA   Rogers J.H., Fawcett J.W.;
RT   "An analysis of astrocytic cell lines with different abilities to
RT   promote axon growth.";
RL   Brain Res. 689:207-223(1995).
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RX   PubMed=8076662; DOI=10.1006/exnr.1994.1127;
RA   Okoye G.S., Freed W.J., Geller H.M.;
RT   "Short-term immunosuppression enhances the survival of intracerebral
RT   grafts of A7-immortalized glial cells.";
RL   Exp. Neurol. 128:191-201(1994).
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RX   PubMed=10516297; DOI=10.1523/JNEUROSCI.19-20-08778.1999; PMCID=PMC6782756;
RA   Fidler P.S., Schuette K., Asher R.A., Dobbertin A., Thornton S.R.,
RA   Calle-Patino Y., Muir E., Levine J.M., Geller H.M., Rogers J.H.,
RA   Faissner A., Fawcett J.W.;
RT   "Comparing astrocytic cell lines that are inhibitory or permissive for
RT   axon growth: the major axon-inhibitory proteoglycan is NG2.";
RL   J. Neurosci. 19:8778-8788(1999).
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