ID   D01
AC   CVCL_DH62
SY   D01-JEB
DR   cancercelllines; CVCL_DH62
DR   Cosmic; 2465279
DR   GEO; GSM170853
DR   GEO; GSM217356
DR   Progenetix; CVCL_DH62
DR   Wikidata; Q54817146
RX   PubMed=17363583;
RX   PubMed=17516929;
RX   PubMed=22383533;
RX   PubMed=23890154;
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=17363583).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=17363583; PubMed=22383533; PubMed=23890154).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   54Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 10-04-25; Version: 14
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RX   PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152;
RA   Stark M.S., Hayward N.K.;
RT   "Genome-wide loss of heterozygosity and copy number analysis in
RT   melanoma using high-density single-nucleotide polymorphism arrays.";
RL   Cancer Res. 67:2632-2642(2007).
//
RX   PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x;
RA   Johansson P., Pavey S., Hayward N.K.;
RT   "Confirmation of a BRAF mutation-associated gene expression signature
RT   in melanoma.";
RL   Pigment Cell Res. 20:216-221(2007).
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RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
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RX   PubMed=23890154; DOI=10.1111/pcmr.12153;
RA   Dutton-Regester K., Kakavand H., Aoude L.G., Stark M.S.,
RA   Gartside M.G., Johansson P., O'Connor L., Lanagan C., Tembe V.,
RA   Pupo G.M., Haydu L.E., Schmidt C.W., Mann G.J., Thompson J.F.,
RA   Scolyer R.A., Hayward N.K.;
RT   "Melanomas of unknown primary have a mutation profile consistent with
RT   cutaneous sun-exposed melanoma.";
RL   Pigment Cell Melanoma Res. 26:852-860(2013).
//