ID   SUM149-Luc/MA1
AC   CVCL_DH45
SY   MA1
DR   cancercelllines; CVCL_DH45
DR   GEO; GSM1463860
DR   GEO; GSM1463863
DR   Wikidata; Q54970829
RX   PubMed=25279830;
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Pro724Leufs*12 (c.2169delT) (p.Asn723fs*13) (2288delT); Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:3373; EP300; Simple; c.4025+26_4025+30 (c.5224+28del3); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>A); ClinVar=VCV000142714; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
DI   NCIt; C4001; Breast inflammatory carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_DH44 ! SUM149-Luc
SX   Female
AG   40Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 14-08-25; Version: 18
//
RX   PubMed=25279830; DOI=10.1371/journal.pone.0109487; PMCID=PMC4184880;
RA   Singh, Balraj
RA   Shamsnia, Anna
RA   Raythatha, Milan Rasik
RA   Milligan, Ryan D.
RA   Cady, Amanda Marie
RA   Madan, Simran
RA   Lucci, Anthony
RT   "Highly adaptable triple-negative breast cancer cells as a functional
RT   model for testing anticancer agents.";
RL   PLoS ONE 9:e109487.1-e109487.14(2014).
//