ID   H1L1.1c7
AC   CVCL_DC21
SY   Hepa.Luc
DR   Wikidata; Q54871987
RX   PubMed=8812260;
CC   Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
CC   Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: C57L.
DI   NCIt; C38756; Hepatocellular carcinoma of the mouse
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0328 ! Hepa-1c1c7
SX   Female
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 29-06-23; Version: 9
//
RX   PubMed=8812260; DOI=10.1006/faat.1996.0152;
RA   Murk A.J., Legler J., Denison M.S., Giesy J.P., van de Guchte C.,
RA   Brouwer A.;
RT   "Chemical-activated luciferase gene expression (CALUX): a novel in
RT   vitro bioassay for Ah receptor active compounds in sediments and pore
RT   water.";
RL   Fundam. Appl. Toxicol. 33:149-160(1996).
//